Project 1: Development of Recombinant Ab-based assay for disease markers
Principal Investigator: Professor Richard O'Kennedy
Overview
This project will involve the development and use of recombinant antibodies in high sensitivity assay formats. The biomarkers involved are C-reactive protein and troponins, markers of cardiac disease and prostate-specific antigen, a marker of prostate cancer. The methodologies used will include molecular biological techniques, enzyme-linked immunosorbent assay, biosensor-based methods of analysis protein isolation and biochip development.
Benefits to or Role of Student
The student will join a team of researchers and learn key aspects of research related to cardiac disease and its diagnosis. The inputs of the student will help the progress of the work and they will accomplish a number of tasks, using advanced biological methods. This should greatly excite their interest in research.
How project fits in with overall objective of research group
The Applied Biochemistry Group under the direction of Prof. Richard O' Kennedy at Dublin City University consists of over 30 researchers (Postdoc / Postgrad / technical / student) and they are involved in a range of multidisciplinary projects with collaborators world-wide. This project is a key element of the work of the Biomedical Diagnostics Institute where rapid diagnosis is of significance.
